All feline diagnoses

Your cat was diagnosed with Thymoma. Thymic epithelial tumour. Paraneoplastic syndromes: myasthenia gravis, exfoliative dermatitis. Compare 2 treatment options for cats including Surgical Resection, Radiation Therapy — with survival times, costs, and what to expect during treatment.

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Thymoma

feline

Epithelial

About This Cancer

Thymoma is a tumour arising from the epithelial cells of the thymus — a gland located in the front of the chest that plays a crucial role in the immune system during youth. While the thymus normally shrinks in adulthood, residual thymic tissue can give rise to this tumour. Thymoma is notable for the paraneoplastic syndromes (tumour-related complications) it can produce, including myasthenia gravis (a condition causing muscle weakness, including difficulty swallowing) and a distinctive exfoliative dermatitis (severe flaking skin disease). The tumour itself is often slow-growing, and cats may present with breathing difficulty due to the mass occupying chest space. If the tumour can be completely removed surgically, the prognosis is often good. The paraneoplastic conditions may or may not resolve after tumour removal.

Masaoka-Koga Staging for Thymoma

Staging system for thymomas based on extent and invasion

Stage IEncapsulated
Stage IIInvasion into surrounding tissues
Stage IIIInvasion into neighbouring organs
Stage IVPleural/pericardial dissemination or haematogenous metastases
Prognostic Factors(3)
Masaoka-Koga stageStage I-II: MST 1,366 days. Stage III-IV: MST 454 days (P=0.002, HR 5.67).(Marks et al., 2024)
Perioperative mortality11% perioperative mortality rate — significant surgical risk.(Marks et al., 2024)
Paraneoplastic syndromesMyasthenia gravis and exfoliative dermatitis may resolve after tumour removal.(Marks et al., 2024)
Minimum Workup(6 steps)
1Thoracic radiographs (cranial mediastinal mass)
2CT chest (extent assessment, vascular involvement)
3FNA cytology of mass (CT-guided or ultrasound-guided)
4CBC, chemistry panel
5Acetylcholine receptor antibody titre (myasthenia gravis screening)
6Dermatologic examination (exfoliative dermatitis screening)

Median Survival Time Comparison

How long the average patient survives with each treatment

Bar opacity reflects evidence strength
Surgical Resection
~29.9 mo
Radiation Therapy
See notes
Reading this page: MST (Median Survival Time) is how long the average patient survives with a given treatment. ORR (Overall Response Rate) is the percentage of patients whose tumour shrank or disappeared. CR = Complete Response (tumour gone); PR = Partial Response (tumour shrank). Hover over any abbreviation for a quick explanation.
Strength of Evidence

Each treatment is rated by how much published research supports its use. Solid bars indicate stronger evidence; dashed bars mean less certainty.

StrongLarge published studies with strong agreement among veterinary oncologists.
ModerateWidely used in clinical practice, but supported by smaller or retrospective studies.
IndirectEvidence comes from a different tumour type or species and has been applied here.
LimitedVery little published data is available for this specific treatment.

Please note: All treatment data is sourced from published peer-reviewed literature. Survival times and cost figures are approximate guides. Your pet's individual factors — including tumour grade, stage, and overall health — will influence outcomes and should guide all treatment decisions. The strength-of-evidence rating reflects how much research exists, not how strongly a treatment is recommended. This tool is designed to help you have informed conversations with your veterinary oncologist, not to replace them. Costs shown are US referral centre estimates and may vary significantly by region.