Chondrosarcoma is a cancer of cartilage-producing cells and is the second most common primary bone tumour in dogs after osteosarcoma. It can arise in the limb bones, ribs, nasal cavity, or larynx. Unlike osteosarcoma, chondrosarcoma generally carries a significantly better prognosis because it tends to grow more slowly and spread less readily — especially the low-grade forms. The outlook depends heavily on the tumour's location and microscopic grade: low-grade tumours at accessible sites can often be cured with surgery alone, while high-grade tumours behave more aggressively and may require additional treatment. Nasal chondrosarcoma can respond to radiation therapy. Large breed dogs, particularly Golden Retrievers, appear to be at somewhat higher risk.